There has been a significant increase in the global burden of chronic kidney diseases of uncertain or non-traditional etiologies, primarily in agricultural communities. This condition has variously been referred to as chronic kidney disease of unknown (CKDu) or non-traditional etiology (CKDnt), chronic intersitital nephritis in agricultural communities (CINAC) and Mesoamerican nephropathy (MeN). Although the general presentation of this condition appears to be similar across affected regions, it remains unclear whether this condition represents one common disease or a syndrome of related ones that differ from affected region to region. A number of potential etiologies and pathophysiological mechanisms for this condition have been proposed, but significant debate exists regarding which factor(s) are the most important to the incidence and progression of chronic kidney diseases in these agricultural communities.
The National Institute of Diabetes and Digestive and Kidney Diseases plans to bring together clinicians, basic scientists, epidemiologists, and public health officials to discuss the current gaps in knowledge and to develop a coordinated scientific research agenda leading to a better understanding of the causes and potential treatments of chronic kidney diseases in agricultural communities in an upcoming event in Bethesda, MD on June 25 and 26.Learn more Register for the event Download the flyer
From the National Institute of Diabetes and Digestive and Kidney Diseases